Description
Research Overview
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. It is widely studied in laboratory research for its interactions with tissue remodeling, extracellular matrix biology, angiogenesis, cellular signaling, antioxidant pathways, and gene regulation. GHK readily forms a biologically active complex with copper(II), known as GHK-Cu, which serves as the primary focus of research.
GHK-Cu is an investigational research peptide and has not been approved for therapeutic use in humans. This material is supplied by Marsden Research Labs exclusively for qualified laboratory research applications and is not offered for human or veterinary use.
Chemical Information
| Compound Name | GHK-Cu |
| Common Name | Copper Tripeptide-1 |
| Compound Type | Naturally occurring copper-binding tripeptide |
| Length | 3 amino acids |
| Molecular Weight | Approximately 402 Da (GHK-Cu complex) |
| Amino Acid Sequence | Gly-His-Lys complexed with copper(II). |
Physical Characteristics
| Appearance | Blue to blue-violet lyophilized powder. |
| Solubility | Water soluble under laboratory conditions. |
| Storage | Store frozen at -20°C or below for long-term stability. |
| Stability | Stability depends on laboratory storage conditions, handling, and repeated freeze-thaw exposure. |
Analytical Verification
Every batch offered by Marsden Research Labs is supported by batch-specific analytical verification whenever documentation is available. Analytical testing is performed to verify identity, assess purity, and provide supporting laboratory documentation for individual research batches.
| Identity Verification | Confirmed using Liquid Chromatography–Mass Spectrometry (LC-MS) when available. |
| Purity Analysis | Determined using High-Performance Liquid Chromatography (HPLC). |
| Batch Documentation | Each verified research batch is assigned a unique batch identifier for traceability. |
| Certificate of Analysis (COA) | Available for verified batches and includes analytical testing results when provided. |
| Laboratory Report | Additional laboratory documentation is provided for applicable batches when available. |
Batch-Specific Information
The batch number, purity value, testing date, Certificate of Analysis (COA), and laboratory report displayed near the top of this page correspond to the selected research sample and update automatically when a different batch or package size is selected.
Mechanism of Action
GHK-Cu functions as a biologically active copper-binding peptide that facilitates the transport of copper ions and participates in numerous cellular signaling pathways. Laboratory studies have investigated its influence on extracellular matrix remodeling, collagen synthesis, angiogenesis, antioxidant enzyme activity, inflammatory signaling, and the regulation of gene expression involved in tissue maintenance and repair. The precise molecular mechanisms remain an active area of investigation.
Because of its broad biological activity, GHK-Cu is frequently investigated in regenerative biology, connective tissue research, vascular biology, oxidative stress signaling, and peptide-mediated cellular regulation.
Current Areas of Research
- Extracellular matrix remodeling
- Collagen and elastin biology
- Angiogenesis and vascular biology
- Oxidative stress and antioxidant signaling
- Gene expression regulation
- Connective tissue and regenerative biology
Marsden Research Labs makes no representation regarding clinical outcomes or therapeutic applications.
Laboratory Handling
This material should be handled only by qualified laboratory personnel using appropriate research procedures.
Research samples should be stored according to accepted laboratory practices to preserve compound integrity. Stability may be affected by storage conditions, repeated freeze-thaw cycles, and handling methods.
Research Use Notice
This product is supplied exclusively for laboratory research purposes.
It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, food use, cosmetic use, or consumption of any kind. Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the acquisition and use of research materials.
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