Research Overview
GHK-Cu is a copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine (GHK). GHK is a naturally occurring copper-binding peptide investigated in laboratory research involving copper coordination, extracellular matrix-associated biology, cellular signaling, gene-expression pathways, oxidative-stress responses, and peptide-metal interactions.
GHK-Cu is an investigational research material. This material is supplied by Marsden Research Labs exclusively for qualified laboratory research applications and is not offered for human or veterinary use.
Chemical Information
| Compound Name | GHK-Cu |
| Common Name | Copper Tripeptide-1 |
| Compound Type | Copper(II)-complexed tripeptide |
| Peptide Length | 3 amino acids |
| Molecular Weight | Approximately 404 Da for the Cu-GHK complex; exact molecular characteristics may depend on the chemical form represented in batch documentation. |
| Amino Acid Sequence | Gly-His-Lys (GHK) complexed with copper(II). |
Physical Characteristics
| Appearance | Blue to blue-violet lyophilized powder. |
| Solubility | Water soluble under laboratory conditions. |
| Storage | Store frozen at -20°C or below for long-term laboratory storage. |
| Stability | Stability depends on the characteristics of the research material and may be affected by storage temperature, moisture, light exposure, solution conditions, repeated freeze-thaw cycles, and laboratory handling. |
Analytical Verification
Every batch made available for purchase by Marsden Research Labs is supported by current, batch-specific third-party laboratory documentation. Products are not made available for purchase until applicable testing and Certificate of Analysis (COA) documentation are complete. Additional independent laboratory reports may be published for a batch when available.
| Identity Verification | May include Liquid Chromatography–Mass Spectrometry (LC-MS) or comparable analytical methods. |
| Purity Analysis | May include High-Performance Liquid Chromatography (HPLC) analysis. |
| Batch Traceability | Research batches are assigned unique batch identifiers corresponding to their applicable analytical results and documentation. |
| Certificate of Analysis (COA) | Required for every batch made available for purchase and reflects the analytical results associated with that batch. |
| Laboratory Report | Additional independent laboratory reports may be published for a batch when available. |
Batch-Specific Information
The batch number, analytical results, testing date, Certificate of Analysis (COA), and any additional independent laboratory report displayed near the top of this page correspond to the selected research sample and update automatically when a different batch or package size is selected.
Investigated Molecular Mechanisms
GHK-Cu is investigated as a peptide-metal complex in which the GHK tripeptide coordinates copper(II). Experimental studies have examined GHK-Cu in relation to copper-associated cellular signaling, extracellular matrix regulation, gene-expression pathways, oxidative-stress signaling, and cellular responses involving fibroblast and endothelial model systems.
The compound is also used as a research tool for investigating peptide-metal coordination, extracellular matrix-associated pathways, cellular regulatory mechanisms, and structure-function relationships of biologically active copper complexes.
Current Areas of Research
- Peptide-copper coordination
- Extracellular matrix-associated biology
- Gene-expression pathways
- Oxidative-stress signaling
- Fibroblast and endothelial cell biology
- Peptide-metal structure-function relationships
Marsden Research Labs makes no representation regarding clinical outcomes or therapeutic applications.
Laboratory Handling
This material should be handled only by qualified laboratory personnel using appropriate research procedures.
Research samples should be stored and handled according to accepted laboratory practices appropriate to the research material. Material integrity may be affected by temperature, moisture, light exposure, solution conditions, repeated freeze-thaw cycles, and handling methods.
Research Use Notice
This product is supplied exclusively for laboratory research purposes.
It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, food use, cosmetic use, or consumption of any kind. Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the acquisition and use of research materials.




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