Research Overview
CJC-1295 without DAC, commonly referred to as Modified GRF (1-29) or Mod GRF (1-29), is a synthetic analog of growth hormone-releasing hormone (GHRH). It contains amino acid substitutions designed to increase resistance to enzymatic degradation while retaining the shorter-duration characteristics associated with non-DAC GHRH analogs. It is investigated in laboratory research involving growth hormone-releasing hormone receptor (GHRHR) signaling, hypothalamic-pituitary biology, endocrine pathway regulation, and peptide pharmacology.
CJC-1295 without DAC is an investigational research peptide and has not been approved for therapeutic use in humans. This material is supplied by Marsden Research Labs exclusively for qualified laboratory research applications and is not offered for human or veterinary use.
Chemical Information
| Compound Name | CJC-1295 without DAC |
| Common Name | Modified GRF (1-29) / Mod GRF (1-29) |
| Compound Type | Synthetic growth hormone-releasing hormone (GHRH) analog |
| Length | 29 amino acids |
| Molecular Weight | Approximately 3.3 kDa |
| Structural Characteristics | Modified GHRH(1-29) analog containing amino acid substitutions associated with increased resistance to enzymatic degradation. |
Physical Characteristics
| Appearance | White to off-white lyophilized powder. |
| Solubility | Water soluble under laboratory conditions. |
| Storage | Store frozen at -20°C or below for long-term laboratory storage. |
| Stability | Stability depends on the characteristics of the research material and may be affected by storage temperature, moisture, light exposure, solution conditions, repeated freeze-thaw cycles, and laboratory handling. |
Analytical Verification
Every batch made available for purchase by Marsden Research Labs is supported by current, batch-specific third-party laboratory documentation. Products are not made available for purchase until applicable testing and Certificate of Analysis (COA) documentation are complete. Additional independent laboratory reports may be published for a batch when available.
| Identity Verification | May include Liquid Chromatography–Mass Spectrometry (LC-MS) or comparable analytical methods. |
| Purity Analysis | May include High-Performance Liquid Chromatography (HPLC) analysis. |
| Batch Traceability | Research batches are assigned unique batch identifiers corresponding to their applicable analytical results and documentation. |
| Certificate of Analysis (COA) | Required for every batch made available for purchase and reflects the analytical results associated with that batch. |
| Laboratory Report | Additional independent laboratory reports may be published for a batch when available. |
Batch-Specific Information
The batch number, analytical results, testing date, Certificate of Analysis (COA), and any additional independent laboratory report displayed near the top of this page correspond to the selected research sample and update automatically when a different batch or package size is selected.
Investigated Molecular Mechanisms
CJC-1295 without DAC is investigated as an agonist of the growth hormone-releasing hormone receptor (GHRHR). Experimental systems use the peptide to examine GHRHR-mediated intracellular signaling, hypothalamic-pituitary communication, endocrine pathway regulation, and downstream growth hormone-axis signaling.
Because it does not contain a Drug Affinity Complex, CJC-1295 without DAC is also used in laboratory investigations comparing shorter-duration GHRH analog signaling with albumin-associated, longer-duration peptide systems.
Current Areas of Research
- Growth hormone-releasing hormone receptor (GHRHR) signaling
- Growth hormone-axis regulation
- Hypothalamic-pituitary signaling
- Endocrine pathway biology
- Peptide pharmacokinetics
- GHRH analog structure-function relationships
Marsden Research Labs makes no representation regarding clinical outcomes or therapeutic applications.
Laboratory Handling
This material should be handled only by qualified laboratory personnel using appropriate research procedures.
Research samples should be stored and handled according to accepted laboratory practices appropriate to the research material. Material integrity may be affected by temperature, moisture, light exposure, solution conditions, repeated freeze-thaw cycles, and handling methods.
Research Use Notice
This product is supplied exclusively for laboratory research purposes.
It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, food use, cosmetic use, or consumption of any kind. Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the acquisition and use of research materials.
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