Description
Research Overview
CJC-1295 with DAC is a synthetic analog of growth hormone-releasing hormone (GHRH) engineered with a Drug Affinity Complex (DAC) to extend its biological half-life. It is widely studied in laboratory research for its interactions with the growth hormone-releasing hormone receptor (GHRHR), endocrine signaling, growth hormone secretion, and insulin-like growth factor 1 (IGF-1) regulatory pathways.
CJC-1295 with DAC is an investigational research peptide and has not been approved for therapeutic use in humans. This material is supplied by Marsden Research Labs exclusively for qualified laboratory research applications and is not offered for human or veterinary use.
Chemical Information
| Compound Name | CJC-1295 with DAC |
| Common Name | CJC-1295 DAC |
| Compound Type | Long-acting synthetic growth hormone-releasing hormone (GHRH) analog |
| Length | 30 amino acids (plus Drug Affinity Complex modification) |
| Molecular Weight | Approximately 3.3–3.4 kDa |
| Amino Acid Sequence | Modified GHRH(1–29) analog containing amino acid substitutions and a Drug Affinity Complex (DAC) to extend biological activity. |
Physical Characteristics
| Appearance | White to off-white lyophilized powder. |
| Solubility | Water soluble under laboratory conditions. |
| Storage | Store frozen at -20°C or below for long-term stability. |
| Stability | Stability depends on laboratory storage conditions, handling, and repeated freeze-thaw exposure. |
Analytical Verification
Every batch offered by Marsden Research Labs is supported by batch-specific analytical verification whenever documentation is available. Analytical testing is performed to verify identity, assess purity, and provide supporting laboratory documentation for individual research batches.
| Identity Verification | Confirmed using Liquid Chromatography–Mass Spectrometry (LC-MS) when available. |
| Purity Analysis | Determined using High-Performance Liquid Chromatography (HPLC). |
| Batch Documentation | Each verified research batch is assigned a unique batch identifier for traceability. |
| Certificate of Analysis (COA) | Available for verified batches and includes analytical testing results when provided. |
| Laboratory Report | Additional laboratory documentation is provided for applicable batches when available. |
Batch-Specific Information
The batch number, purity value, testing date, Certificate of Analysis (COA), and laboratory report displayed near the top of this page correspond to the selected research sample and update automatically when a different batch or package size is selected.
Mechanism of Action
CJC-1295 with DAC functions as an agonist of the growth hormone-releasing hormone receptor (GHRHR) located on anterior pituitary somatotroph cells. Activation of this receptor stimulates endogenous growth hormone secretion, resulting in downstream activation of insulin-like growth factor 1 (IGF-1) signaling. The Drug Affinity Complex (DAC) enables reversible binding to circulating albumin, substantially extending the peptide’s biological half-life compared to shorter-acting GHRH analogs.
Because of its prolonged biological activity, CJC-1295 with DAC is frequently investigated in endocrine physiology, growth hormone regulation, peptide pharmacokinetics, and metabolic signaling research.
Current Areas of Research
- Growth hormone-releasing hormone (GHRH) receptor signaling
- Endogenous growth hormone secretion
- IGF-1 pathway regulation
- Endocrine system research
- Long-acting peptide pharmacology
- Metabolic pathway investigation
Marsden Research Labs makes no representation regarding clinical outcomes or therapeutic applications.
Laboratory Handling
This material should be handled only by qualified laboratory personnel using appropriate research procedures.
Research samples should be stored according to accepted laboratory practices to preserve compound integrity. Stability may be affected by storage conditions, repeated freeze-thaw cycles, and handling methods.
Research Use Notice
This product is supplied exclusively for laboratory research purposes.
It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, food use, cosmetic use, or consumption of any kind. Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the acquisition and use of research materials.
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