Description
Research Overview
MK-677, also known as Ibutamoren Mesylate, is a non-peptide small-molecule growth hormone secretagogue. It is widely studied in laboratory research for its interactions with the growth hormone secretagogue receptor (GHSR-1a), endocrine signaling, growth hormone regulation, insulin-like growth factor-1 (IGF-1) signaling, appetite regulation, and metabolic physiology.
Although commonly grouped with peptide research compounds, MK-677 is not a peptide. It is an investigational research compound and has not been approved for therapeutic use in humans for the indications commonly studied in research. This material is supplied by Marsden Research Labs exclusively for qualified laboratory research applications and is not offered for human or veterinary use.
Chemical Information
| Compound Name | Ibutamoren Mesylate |
| Common Name | MK-677 |
| Compound Type | Non-peptide growth hormone secretagogue |
| Chemical Formula | C28H40N4O8S (mesylate salt) |
| Molecular Weight | Approximately 624.8 Da (mesylate salt) |
| Classification | Orally active ghrelin receptor agonist for laboratory research. |
Physical Characteristics
| Appearance | White to off-white crystalline or lyophilized powder. |
| Solubility | Solubility depends on laboratory solvent system and formulation. |
| Storage | Store frozen at -20°C or below for long-term stability. Protect from moisture and light. |
| Stability | Stability depends on laboratory storage conditions, handling, and environmental exposure. |
Analytical Verification
Every batch offered by Marsden Research Labs is supported by batch-specific analytical verification whenever documentation is available. Analytical testing is performed to verify identity, assess purity, and provide supporting laboratory documentation for individual research batches.
| Identity Verification | Confirmed using Liquid Chromatography–Mass Spectrometry (LC-MS) when available. |
| Purity Analysis | Determined using High-Performance Liquid Chromatography (HPLC). |
| Batch Documentation | Each verified research batch is assigned a unique batch identifier for traceability. |
| Certificate of Analysis (COA) | Available for verified batches and includes analytical testing results when provided. |
| Laboratory Report | Additional laboratory documentation is provided for applicable batches when available. |
Batch-Specific Information
The batch number, purity value, testing date, Certificate of Analysis (COA), and laboratory report displayed near the top of this page correspond to the selected research sample and update automatically when a different batch or package size is selected.
Mechanism of Action
MK-677 functions as a selective agonist of the growth hormone secretagogue receptor (GHSR-1a), commonly known as the ghrelin receptor. Activation of this receptor stimulates intracellular signaling pathways involved in endogenous growth hormone secretion and subsequent insulin-like growth factor-1 (IGF-1) production. Laboratory investigations also examine its effects on appetite regulation, energy homeostasis, endocrine physiology, and metabolic signaling.
Because of its biological activity, MK-677 is frequently investigated in growth hormone physiology, ghrelin receptor pharmacology, IGF-1 signaling, metabolic regulation, appetite biology, and endocrine research.
Current Areas of Research
- Growth hormone secretagogue receptor (GHSR) signaling
- Insulin-like growth factor-1 (IGF-1) regulation
- Growth hormone physiology
- Ghrelin receptor pharmacology
- Appetite and energy homeostasis
- Metabolic pathway investigation
Marsden Research Labs makes no representation regarding clinical outcomes or therapeutic applications.
Laboratory Handling
This material should be handled only by qualified laboratory personnel using appropriate research procedures.
Research samples should be stored according to accepted laboratory practices to preserve compound integrity. Stability may be affected by storage conditions, moisture exposure, and handling methods.
Research Use Notice
This product is supplied exclusively for laboratory research purposes.
It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, food use, cosmetic use, or consumption of any kind. Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the acquisition and use of research materials.
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