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Research Overview
Kisspeptin-10 (KP-10) is a synthetic decapeptide corresponding to the biologically active C-terminal region of the human KISS1-derived kisspeptin peptide. It is investigated in laboratory systems involving kisspeptin receptor (KISS1R/GPR54) signaling, neuroendocrine communication, hypothalamic-pituitary-gonadal (HPG) axis biology, G protein-coupled receptor pharmacology, and peptide-mediated intracellular signaling.
Kisspeptin-10 is an investigational research peptide and has not been approved for therapeutic use in humans. This material is supplied by Marsden Research Labs exclusively for qualified laboratory research applications and is not offered for human or veterinary use.
Chemical Information
| Compound Name | Kisspeptin-10 |
| Common Name | KP-10 |
| CAS Number | 374675-21-5 |
| Compound Type | Synthetic KISS1-derived neuroendocrine peptide |
| Length | 10 amino acids |
| Chemical Formula | C63H83N17O14 |
| Molecular Weight | Approximately 1302.4 g/mol |
| Amino Acid Sequence | Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 |
Physical Characteristics
| Appearance | White to off-white lyophilized powder. |
| Solubility | Water soluble under laboratory conditions. |
| Storage | Store frozen at -20°C or below for long-term laboratory storage. |
| Stability | Stability depends on the characteristics of the research material and may be affected by storage temperature, moisture, light exposure, solution conditions, repeated freeze-thaw cycles, and laboratory handling. |
Analytical Verification
Every batch made available for purchase by Marsden Research Labs is supported by current, batch-specific third-party laboratory documentation. Products are not made available for purchase until applicable testing and Certificate of Analysis (COA) documentation are complete. Additional independent laboratory reports may be published for a batch when available.
| Identity Verification | May include Liquid Chromatography–Mass Spectrometry (LC-MS) or comparable analytical methods. |
| Purity Analysis | May include High-Performance Liquid Chromatography (HPLC) analysis. |
| Quantitative Analysis | May include quantitative assessment appropriate to the individual batch and analytical method. |
| Batch Traceability | Research batches are assigned unique batch identifiers corresponding to their applicable analytical results and documentation. |
| Certificate of Analysis (COA) | Required for every batch made available for purchase and reflects the analytical results associated with that batch. |
| Laboratory Report | Additional independent laboratory reports may be published for a batch when available. |
Batch-Specific Information
The batch number, analytical results, testing date, Certificate of Analysis (COA), and any additional independent laboratory report displayed near the top of this page correspond to the selected research sample and update automatically when a different batch or package size is selected.
Investigated Molecular Mechanisms
Kisspeptin-10 is investigated as an agonist of the kisspeptin receptor (KISS1R/GPR54), a G protein-coupled receptor involved in neuroendocrine signaling. Experimental systems use Kisspeptin-10 to examine receptor activation, Gq/11-associated intracellular signaling, phospholipase C-linked pathways, and hypothalamic neuroendocrine communication.
Kisspeptin-10 is also used as a research tool for investigating KISS1R receptor pharmacology, HPG-axis signaling networks, peptide-receptor interactions, and structure-function relationships within the kisspeptin signaling system.
Current Areas of Research
- Kisspeptin receptor (KISS1R/GPR54) signaling
- G protein-coupled receptor pharmacology
- Gq/11-associated intracellular signaling
- Hypothalamic neuroendocrine communication
- HPG-axis signaling biology
- Kisspeptin peptide structure-function relationships
Marsden Research Labs makes no representation regarding clinical outcomes or therapeutic applications.
Laboratory Handling
This material should be handled only by qualified laboratory personnel using appropriate research procedures.
Research samples should be stored and handled according to accepted laboratory practices appropriate to the research material. Material integrity may be affected by temperature, moisture, light exposure, solution conditions, repeated freeze-thaw cycles, and handling methods.
Research Use Notice
This product is supplied exclusively for laboratory research purposes.
It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, food use, cosmetic use, or consumption of any kind. Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the acquisition and use of research materials.
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