Description
Research Overview
TB-500 is a synthetic peptide that corresponds to the biologically active region of Thymosin Beta-4 (Tβ4), a naturally occurring actin-binding protein widely distributed throughout mammalian tissues. It is extensively studied in laboratory research for its interactions with actin dynamics, cellular migration, angiogenesis, extracellular matrix remodeling, and tissue regeneration pathways.
TB-500 is an investigational research peptide and has not been approved for therapeutic use in humans. This material is supplied by Marsden Research Labs exclusively for qualified laboratory research applications and is not offered for human or veterinary use.
Chemical Information
| Compound Name | TB-500 |
| Common Name | TB-500 |
| Compound Type | Synthetic Thymosin Beta-4 peptide fragment |
| Length | 43 amino acids |
| Molecular Weight | Approximately 4.96 kDa |
| Classification | Synthetic actin-binding research peptide derived from Thymosin Beta-4. |
Physical Characteristics
| Appearance | White to off-white lyophilized powder. |
| Solubility | Water soluble under laboratory conditions. |
| Storage | Store frozen at -20°C or below for long-term stability. |
| Stability | Stability depends on laboratory storage conditions, handling, and repeated freeze-thaw exposure. |
Analytical Verification
Every batch offered by Marsden Research Labs is supported by batch-specific analytical verification whenever documentation is available. Analytical testing is performed to verify identity, assess purity, and provide supporting laboratory documentation for individual research batches.
| Identity Verification | Confirmed using Liquid Chromatography–Mass Spectrometry (LC-MS) when available. |
| Purity Analysis | Determined using High-Performance Liquid Chromatography (HPLC). |
| Batch Documentation | Each verified research batch is assigned a unique batch identifier for traceability. |
| Certificate of Analysis (COA) | Available for verified batches and includes analytical testing results when provided. |
| Laboratory Report | Additional laboratory documentation is provided for applicable batches when available. |
Batch-Specific Information
The batch number, purity value, testing date, Certificate of Analysis (COA), and laboratory report displayed near the top of this page correspond to the selected research sample and update automatically when a different batch or package size is selected.
Mechanism of Action
TB-500 is derived from the naturally occurring protein Thymosin Beta-4 and has been extensively investigated for its interactions with G-actin, an essential component of the cellular cytoskeleton. Laboratory studies have examined its influence on actin polymerization, cellular migration, angiogenesis, extracellular matrix remodeling, and tissue organization. Through modulation of cytoskeletal dynamics, TB-500 serves as an important research tool for studying cellular movement, wound biology, and regenerative signaling pathways.
Because of its biological activity, TB-500 is frequently investigated in actin dynamics, connective tissue biology, angiogenesis, extracellular matrix remodeling, cellular migration, and regenerative physiology.
Current Areas of Research
- Actin polymerization and cytoskeletal dynamics
- Cell migration and tissue remodeling
- Angiogenesis and vascular biology
- Extracellular matrix regulation
- Connective tissue biology
- Regenerative signaling pathways
Marsden Research Labs makes no representation regarding clinical outcomes or therapeutic applications.
Laboratory Handling
This material should be handled only by qualified laboratory personnel using appropriate research procedures.
Research samples should be stored according to accepted laboratory practices to preserve compound integrity. Stability may be affected by storage conditions, repeated freeze-thaw cycles, and handling methods.
Research Use Notice
This product is supplied exclusively for laboratory research purposes.
It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, food use, cosmetic use, or consumption of any kind. Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the acquisition and use of research materials.
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