Description
Research Overview
Vasoactive Intestinal Peptide (VIP) is a naturally occurring 28-amino acid neuropeptide belonging to the secretin/glucagon peptide family. It is widely distributed throughout the central and peripheral nervous systems and is extensively studied in laboratory research for its interactions with VIP receptors (VPAC1 and VPAC2), neuroimmune signaling, smooth muscle physiology, inflammatory pathways, and cellular communication.
VIP is an investigational research peptide and has not been approved for therapeutic use in humans for the indications commonly studied in research. This material is supplied by Marsden Research Labs exclusively for qualified laboratory research applications and is not offered for human or veterinary use.
Chemical Information
| Compound Name | Vasoactive Intestinal Peptide |
| Common Name | VIP |
| Compound Type | Endogenous neuropeptide |
| Length | 28 amino acids |
| Molecular Weight | Approximately 3.3 kDa |
| Classification | Secretin/glucagon family neuropeptide. |
Physical Characteristics
| Appearance | White to off-white lyophilized powder. |
| Solubility | Water soluble under laboratory conditions. |
| Storage | Store frozen at -20°C or below for long-term stability. |
| Stability | Stability depends on laboratory storage conditions, handling, and repeated freeze-thaw exposure. |
Analytical Verification
Every batch offered by Marsden Research Labs is supported by batch-specific analytical verification whenever documentation is available. Analytical testing is performed to verify identity, assess purity, and provide supporting laboratory documentation for individual research batches.
| Identity Verification | Confirmed using Liquid Chromatography–Mass Spectrometry (LC-MS) when available. |
| Purity Analysis | Determined using High-Performance Liquid Chromatography (HPLC). |
| Batch Documentation | Each verified research batch is assigned a unique batch identifier for traceability. |
| Certificate of Analysis (COA) | Available for verified batches and includes analytical testing results when provided. |
| Laboratory Report | Additional laboratory documentation is provided for applicable batches when available. |
Batch-Specific Information
The batch number, purity value, testing date, Certificate of Analysis (COA), and laboratory report displayed near the top of this page correspond to the selected research sample and update automatically when a different batch or package size is selected.
Mechanism of Action
VIP functions as an agonist of the VPAC1 and VPAC2 receptors, members of the class B G protein-coupled receptor family. Activation of these receptors stimulates cyclic adenosine monophosphate (cAMP)-dependent signaling pathways involved in smooth muscle physiology, neuroimmune communication, cytokine regulation, vasoregulatory signaling, and cellular homeostasis. Laboratory investigations utilize VIP to study neuropeptide signaling, receptor pharmacology, inflammatory biology, and communication between the nervous and immune systems.
Because of its biological activity, VIP is frequently investigated in neuroimmune signaling, VPAC receptor pharmacology, inflammatory pathway regulation, smooth muscle physiology, autonomic nervous system function, and peptide-mediated cellular communication.
Current Areas of Research
- VPAC1 and VPAC2 receptor signaling
- Neuroimmune communication
- Inflammatory signaling pathways
- Autonomic nervous system physiology
- Smooth muscle biology
- cAMP-mediated cellular signaling
Marsden Research Labs makes no representation regarding clinical outcomes or therapeutic applications.
Laboratory Handling
This material should be handled only by qualified laboratory personnel using appropriate research procedures.
Research samples should be stored according to accepted laboratory practices to preserve compound integrity. Stability may be affected by storage conditions, repeated freeze-thaw cycles, and handling methods.
Research Use Notice
This product is supplied exclusively for laboratory research purposes.
It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, food use, cosmetic use, or consumption of any kind. Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the acquisition and use of research materials.
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