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Research Overview
Cagrilintide is a synthetic, lipidated amylin analog developed for laboratory investigation of calcitonin-family receptor pharmacology, peptide hormone signaling, metabolic pathways, and amylin-associated signaling systems. Its structural modifications are designed to increase molecular stability and extend biological activity relative to native amylin.
Cagrilintide is an investigational research compound. This material is supplied by Marsden Research Labs exclusively for qualified laboratory research applications and is not offered for human or veterinary use.
Chemical Information
| Compound Name | Cagrilintide |
| Alternative Name | AM833 / NN0174-0833 |
| CAS Number | 1415456-99-3 |
| Compound Type | Synthetic lipidated amylin analog |
| Chemical Formula | C194H312N54O59S2 |
| Molecular Weight | Approximately 4.41 kDa |
| Structural Characteristics | Modified amylin analog containing a disulfide-linked peptide sequence and lipid-associated structural modification. |
Physical Characteristics
| Appearance | White to off-white lyophilized powder. |
| Solubility | Water soluble under laboratory conditions. |
| Storage | Store frozen at -20°C or below for long-term laboratory storage. |
| Stability | Stability depends on the characteristics of the research material and may be affected by storage temperature, moisture, light exposure, solution conditions, repeated freeze-thaw cycles, and laboratory handling. |
Analytical Verification
Every batch made available for purchase by Marsden Research Labs is supported by current, batch-specific third-party laboratory documentation. Products are not made available for purchase until applicable testing and Certificate of Analysis (COA) documentation are complete. Additional independent laboratory reports may be published for a batch when available.
| Identity Verification | May include Liquid Chromatography–Mass Spectrometry (LC-MS) or comparable analytical methods. |
| Purity Analysis | May include High-Performance Liquid Chromatography (HPLC) analysis. |
| Batch Traceability | Research batches are assigned unique batch identifiers corresponding to their applicable analytical results and documentation. |
| Certificate of Analysis (COA) | Required for every batch made available for purchase and reflects the analytical results associated with that batch. |
| Laboratory Report | Additional independent laboratory reports may be published for a batch when available. |
Batch-Specific Information
The batch number, analytical results, testing date, Certificate of Analysis (COA), and any additional independent laboratory report displayed near the top of this page correspond to the selected research sample and update automatically when a different batch or package size is selected.
Investigated Molecular Mechanisms
Cagrilintide is investigated as an agonist of calcitonin-family receptors, including amylin receptor complexes and the calcitonin receptor. These receptor systems are studied in experimental models involving G protein-coupled receptor signaling, cyclic AMP pathways, peptide hormone pharmacology, and metabolic signaling.
Cagrilintide is therefore used as a research tool for investigating amylin-associated receptor biology, calcitonin-family receptor pharmacology, peptide signaling, and cellular metabolic pathways.
Current Areas of Research
- Amylin receptor signaling
- Calcitonin-family receptor pharmacology
- G protein-coupled receptor signaling
- Peptide hormone biology
- Metabolic signaling pathways
- Structure-function relationships of lipidated peptides
Marsden Research Labs makes no representation regarding clinical outcomes or therapeutic applications.
Laboratory Handling
This material should be handled only by qualified laboratory personnel using appropriate research procedures.
Research samples should be stored and handled according to accepted laboratory practices appropriate to the research material. Material integrity may be affected by temperature, moisture, light exposure, solution conditions, repeated freeze-thaw cycles, and handling methods.
Research Use Notice
This product is supplied exclusively for laboratory research purposes.
It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, food use, cosmetic use, or consumption of any kind. Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the acquisition and use of research materials.
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