Description
Research Overview
Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH 4–10) with structural modifications that improve stability while eliminating hormonal activity associated with the parent peptide. It is widely studied in laboratory research for its interactions with neuropeptide signaling, central nervous system function, neurotrophic factor regulation, neurotransmitter systems, and neuroendocrine physiology.
Semax is an investigational research peptide and has not been approved for therapeutic use in humans. This material is supplied by Marsden Research Labs exclusively for qualified laboratory research applications and is not offered for human or veterinary use.
Chemical Information
| Compound Name | Semax |
| Common Name | Semax |
| Compound Type | Synthetic heptapeptide |
| Length | 7 amino acids |
| Molecular Weight | Approximately 814 Da |
| Amino Acid Sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
Physical Characteristics
| Appearance | White to off-white lyophilized powder. |
| Solubility | Water soluble under laboratory conditions. |
| Storage | Store frozen at -20°C or below for long-term stability. |
| Stability | Stability depends on laboratory storage conditions, handling, and repeated freeze-thaw exposure. |
Analytical Verification
Every batch offered by Marsden Research Labs is supported by batch-specific analytical verification whenever documentation is available. Analytical testing is performed to verify identity, assess purity, and provide supporting laboratory documentation for individual research batches.
| Identity Verification | Confirmed using Liquid Chromatography–Mass Spectrometry (LC-MS) when available. |
| Purity Analysis | Determined using High-Performance Liquid Chromatography (HPLC). |
| Batch Documentation | Each verified research batch is assigned a unique batch identifier for traceability. |
| Certificate of Analysis (COA) | Available for verified batches and includes analytical testing results when provided. |
| Laboratory Report | Additional laboratory documentation is provided for applicable batches when available. |
Batch-Specific Information
The batch number, purity value, testing date, Certificate of Analysis (COA), and laboratory report displayed near the top of this page correspond to the selected research sample and update automatically when a different batch or package size is selected.
Mechanism of Action
Semax has been investigated for its interactions with multiple neurochemical systems involved in neuronal signaling and neuroplasticity. Laboratory studies have examined its influence on brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), dopaminergic and serotonergic signaling, glutamatergic neurotransmission, and intracellular pathways associated with neuronal adaptation. Although its precise molecular mechanisms continue to be investigated, Semax is widely used as a research tool for studying neuropeptide-mediated communication within the central nervous system.
Because of its biological activity, Semax is frequently investigated in neuropeptide biology, neurotrophic factor regulation, neurotransmitter signaling, neuroplasticity, and central nervous system physiology.
Current Areas of Research
- Neuropeptide signaling
- Brain-derived neurotrophic factor (BDNF) regulation
- Nerve growth factor (NGF) biology
- Neurotransmitter signaling pathways
- Neuroplasticity research
- Central nervous system physiology
Marsden Research Labs makes no representation regarding clinical outcomes or therapeutic applications.
Laboratory Handling
This material should be handled only by qualified laboratory personnel using appropriate research procedures.
Research samples should be stored according to accepted laboratory practices to preserve compound integrity. Stability may be affected by storage conditions, repeated freeze-thaw cycles, and handling methods.
Research Use Notice
This product is supplied exclusively for laboratory research purposes.
It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, food use, cosmetic use, or consumption of any kind. Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the acquisition and use of research materials.
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