Description
Research Overview
Sermorelin is a synthetic peptide corresponding to the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH 1–29), the biologically active region responsible for stimulating growth hormone release. It is widely studied in laboratory research for its interactions with the growth hormone-releasing hormone receptor (GHRHR), hypothalamic-pituitary signaling, endocrine physiology, and growth hormone regulation.
Sermorelin is an investigational research peptide and has not been approved for therapeutic use in humans. This material is supplied by Marsden Research Labs exclusively for qualified laboratory research applications and is not offered for human or veterinary use.
Chemical Information
| Compound Name | Sermorelin |
| Common Name | GHRH (1–29) |
| Compound Type | Synthetic growth hormone-releasing hormone analog |
| Length | 29 amino acids |
| Molecular Weight | Approximately 3.36 kDa |
| Structure | Synthetic peptide corresponding to the biologically active N-terminal region of endogenous human growth hormone-releasing hormone. |
Physical Characteristics
| Appearance | White to off-white lyophilized powder. |
| Solubility | Water soluble under laboratory conditions. |
| Storage | Store frozen at -20°C or below for long-term stability. |
| Stability | Stability depends on laboratory storage conditions, handling, and repeated freeze-thaw exposure. |
Analytical Verification
Every batch offered by Marsden Research Labs is supported by batch-specific analytical verification whenever documentation is available. Analytical testing is performed to verify identity, assess purity, and provide supporting laboratory documentation for individual research batches.
| Identity Verification | Confirmed using Liquid Chromatography–Mass Spectrometry (LC-MS) when available. |
| Purity Analysis | Determined using High-Performance Liquid Chromatography (HPLC). |
| Batch Documentation | Each verified research batch is assigned a unique batch identifier for traceability. |
| Certificate of Analysis (COA) | Available for verified batches and includes analytical testing results when provided. |
| Laboratory Report | Additional laboratory documentation is provided for applicable batches when available. |
Batch-Specific Information
The batch number, purity value, testing date, Certificate of Analysis (COA), and laboratory report displayed near the top of this page correspond to the selected research sample and update automatically when a different batch or package size is selected.
Mechanism of Action
Sermorelin functions as an agonist of the growth hormone-releasing hormone receptor (GHRHR) located on anterior pituitary somatotroph cells. Activation of this receptor stimulates cyclic adenosine monophosphate (cAMP) signaling and promotes endogenous growth hormone secretion. Laboratory investigations utilize Sermorelin to study hypothalamic-pituitary communication, endocrine regulation, growth hormone physiology, and downstream insulin-like growth factor-1 (IGF-1) signaling pathways.
Because of its biological activity, Sermorelin is frequently investigated in endocrine physiology, growth hormone-releasing hormone receptor signaling, hypothalamic-pituitary function, peptide hormone biology, and IGF-1 regulation.
Current Areas of Research
- Growth hormone-releasing hormone receptor (GHRHR) signaling
- Hypothalamic-pituitary physiology
- Endogenous growth hormone regulation
- Insulin-like growth factor-1 (IGF-1) signaling
- Endocrine system research
- Peptide hormone pharmacology
Marsden Research Labs makes no representation regarding clinical outcomes or therapeutic applications.
Laboratory Handling
This material should be handled only by qualified laboratory personnel using appropriate research procedures.
Research samples should be stored according to accepted laboratory practices to preserve compound integrity. Stability may be affected by storage conditions, repeated freeze-thaw cycles, and handling methods.
Research Use Notice
This product is supplied exclusively for laboratory research purposes.
It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, food use, cosmetic use, or consumption of any kind. Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the acquisition and use of research materials.
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