Description
Research Overview
SS-31, also known as Elamipretide, is a synthetic mitochondria-targeting tetrapeptide designed to selectively localize within the inner mitochondrial membrane. It is widely studied in laboratory research for its interactions with mitochondrial membranes, cardiolipin, oxidative phosphorylation, cellular bioenergetics, and mitochondrial signaling. SS-31 has become an important research tool for investigating mitochondrial function and cellular energy homeostasis.
SS-31 is an investigational research peptide and has not been approved for therapeutic use in humans. This material is supplied by Marsden Research Labs exclusively for qualified laboratory research applications and is not offered for human or veterinary use.
Chemical Information
| Compound Name | Elamipretide |
| Common Name | SS-31 |
| Compound Type | Synthetic mitochondria-targeting tetrapeptide |
| Length | 4 amino acids |
| Molecular Weight | Approximately 640 Da |
| Amino Acid Sequence | D-Arg-Dmt-Lys-Phe-NH2 (Dmt = 2′,6′-dimethyltyrosine) |
Physical Characteristics
| Appearance | White to off-white lyophilized powder. |
| Solubility | Water soluble under laboratory conditions. |
| Storage | Store frozen at -20°C or below for long-term stability. |
| Stability | Stability depends on laboratory storage conditions, handling, and repeated freeze-thaw exposure. |
Analytical Verification
Every batch offered by Marsden Research Labs is supported by batch-specific analytical verification whenever documentation is available. Analytical testing is performed to verify identity, assess purity, and provide supporting laboratory documentation for individual research batches.
| Identity Verification | Confirmed using Liquid Chromatography–Mass Spectrometry (LC-MS) when available. |
| Purity Analysis | Determined using High-Performance Liquid Chromatography (HPLC). |
| Batch Documentation | Each verified research batch is assigned a unique batch identifier for traceability. |
| Certificate of Analysis (COA) | Available for verified batches and includes analytical testing results when provided. |
| Laboratory Report | Additional laboratory documentation is provided for applicable batches when available. |
Batch-Specific Information
The batch number, purity value, testing date, Certificate of Analysis (COA), and laboratory report displayed near the top of this page correspond to the selected research sample and update automatically when a different batch or package size is selected.
Mechanism of Action
SS-31 selectively associates with cardiolipin, a phospholipid located within the inner mitochondrial membrane. Laboratory investigations have shown that this interaction may influence mitochondrial membrane architecture, electron transport chain efficiency, oxidative phosphorylation, reactive oxygen species (ROS) production, and ATP generation. SS-31 is widely utilized as a research tool for studying mitochondrial bioenergetics, cellular stress responses, and mitochondrial membrane biology.
Because of its biological activity, SS-31 is frequently investigated in mitochondrial physiology, cellular bioenergetics, oxidative stress, cardiolipin biology, energy metabolism, and mitochondrial signaling pathways.
Current Areas of Research
- Mitochondrial membrane biology
- Cardiolipin interactions
- Oxidative phosphorylation
- Cellular bioenergetics
- Reactive oxygen species (ROS) regulation
- Mitochondrial signaling pathways
Marsden Research Labs makes no representation regarding clinical outcomes or therapeutic applications.
Laboratory Handling
This material should be handled only by qualified laboratory personnel using appropriate research procedures.
Research samples should be stored according to accepted laboratory practices to preserve compound integrity. Stability may be affected by storage conditions, repeated freeze-thaw cycles, and handling methods.
Research Use Notice
This product is supplied exclusively for laboratory research purposes.
It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, food use, cosmetic use, or consumption of any kind. Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the acquisition and use of research materials.
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