Research Overview
SS-31, also known as Elamipretide, is a synthetic aromatic-cationic tetrapeptide investigated in laboratory systems involving mitochondrial membrane biology, cardiolipin interactions, inner mitochondrial membrane organization, mitochondrial signaling, and peptide-lipid interactions.
Elamipretide has been developed as a mitochondria-targeting peptide and provides an experimental model for investigating interactions between short synthetic peptides and cardiolipin-containing membrane systems.
Elamipretide is an established pharmaceutical active substance. The SS-31 material offered by Marsden Research Labs is supplied exclusively for qualified laboratory research applications and is not offered as a pharmaceutical product or for human or veterinary use.
Chemical Information
| Compound Name | Elamipretide |
| Common Name | SS-31 |
| Compound Type | Synthetic mitochondria-targeting tetrapeptide |
| Length | 4 amino-acid residues |
| Chemical Formula | C32H49N9O5 (free base) |
| Molecular Weight | Approximately 639.79 g/mol for elamipretide free base. |
| Peptide Sequence | D-Arg-Dmt-Lys-Phe-NH2 Dmt = 2,6-dimethyltyrosine |
Physical Characteristics
| Appearance | White to off-white lyophilized material. |
| Solubility | Solubility characteristics depend on chemical form, concentration, pH, and laboratory conditions. |
| Storage | Store under appropriate laboratory conditions with protection from unnecessary heat, moisture, and light exposure. |
| Stability | Stability depends on the characteristics of the research material and may be affected by storage temperature, moisture, light exposure, solution conditions, repeated freeze-thaw cycles, and laboratory handling. |
Analytical Verification
Every batch made available for purchase by Marsden Research Labs is supported by current, batch-specific third-party laboratory documentation. Products are not made available for purchase until applicable testing and Certificate of Analysis (COA) documentation are complete. Additional independent laboratory reports may be published for a batch when available.
| Identity Verification | May include Liquid Chromatography–Mass Spectrometry (LC-MS) or comparable analytical methods. |
| Purity Analysis | May include High-Performance Liquid Chromatography (HPLC) or other analytical methods appropriate to the individual sample. |
| Quantitative Analysis | May include quantitative assessment appropriate to the individual batch and analytical method. |
| Batch Traceability | Research batches are assigned unique batch identifiers corresponding to their applicable analytical results and documentation. |
| Certificate of Analysis (COA) | Required for every batch made available for purchase and reflects the analytical results associated with that batch. |
| Laboratory Report | Additional independent laboratory reports may be published for a batch when available. |
Batch-Specific Information
The batch number, analytical results, testing date, Certificate of Analysis (COA), and any additional independent laboratory report displayed near the top of this page correspond to the selected research sample and update automatically when a different batch or package size is selected.
Investigated Molecular Mechanisms
Elamipretide is investigated as a cardiolipin-binding peptide that localizes to the inner mitochondrial membrane. Experimental systems use SS-31 to examine peptide-lipid interactions, cardiolipin-associated membrane organization, mitochondrial membrane properties, and relationships between cardiolipin and mitochondrial protein systems.
Because cardiolipin is closely associated with the organization of proteins within the inner mitochondrial membrane, SS-31 provides a research model for investigating mitochondrial membrane architecture, cardiolipin-dependent signaling systems, and the influence of peptide-lipid interactions on mitochondrial cellular processes.
Current Areas of Research
- Cardiolipin-peptide interactions
- Inner mitochondrial membrane biology
- Mitochondrial membrane organization
- Peptide-lipid binding interactions
- Mitochondrial signaling systems
- Cardiolipin-associated protein organization
- Mitochondria-targeting peptide structure-function relationships
Marsden Research Labs makes no representation regarding clinical outcomes or therapeutic applications.
Laboratory Handling
This material should be handled only by qualified laboratory personnel using appropriate research procedures.
Research samples should be stored and handled according to accepted laboratory practices appropriate to the research material. Material integrity may be affected by temperature, moisture, light exposure, solution conditions, repeated freeze-thaw cycles, and handling methods.
Research Use Notice
This product is supplied exclusively for laboratory research purposes.
It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, food use, cosmetic use, or consumption of any kind. Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the acquisition and use of research materials.
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